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Before IVF- What is intrauterine insemination?

What is IUI?

Intrauterine insemination (IUI) involves a laboratory procedure to separate fast moving sperm from more sluggish or non-moving sperm.The fast moving sperm are then placed into the woman’s womb close to the time of ovulation when the egg is released from the ovary in the middle of the monthly cycle.

Is IUI for me?

Your doctor may recommend IUI if:

  • there is unexplained infertility
  • there are ovulation problems
  • the male partner experiences impotence or low sperm count or decreased sperm mobility
  • you do not have any known fertility problems but may not have a male partner and are trying for a baby using donated sperm.
  • Ejaculation dysfunction


In sum, IUI is a reasonable therapy for some infertility patients, but should be abandoned for IVF by the end of the third IUI cycle.

It is essential that your fallopian tubes are known to be open and healthy before the IUI process begins, because one of the most common causes of infertility is blockage of the fallopian tubes. A tubal patency test is usually carried out as part of your assessment by the fertility clinic. When the pelvis and tubes are healthy, dye passes freely through both tubes. There should be no adhesions present that might prevent an egg from having access to either tube from the ovaries.


The second essential requirement is that there is no significant problem with sperm numbers or sperm quality. If your partner is unable to provide sperm, or if you do not have a male partner, you may want to consider donated sperm.


How does IUI work?

For women:

  • If you are not using fertility drugs IUI is done between day 12 and day 16 of your monthly cycle – with day one being the first day of your period. You are given blood or urine tests to identify when you are about to ovulate. Many clinics will provide you with an ovulation predictor kit to detect the hormone surge that signals imminent ovulation.

– or –

If you use fertility drugs to stimulate ovulation, vaginal ultrasound scans are used to track the development of your eggs. As soon as an egg is mature, you are given a hormone injection to stimulate its release.

You should consider the best option for you with your doctor.


  •  The sperm are inserted 36 to 40 hours later. To do this, the doctor first  inserts a speculum (a special instrument that keeps your vaginal walls apart) into your vagina.

A small catheter (a soft, flexible tube) is then threaded into your womb via your cervix. The best quality sperm are selected and inserted through the catheter.

The whole process takes just a few minutes and is usually a painless procedure but some women may experience a temporary, menstrual-like cramping.

  • You may want to rest for a short time before leaving the clinic – ask your clinic what they recommend.


For men:

  • You will be asked to produce a sperm sample on the day the treatment takes place.
  • The sperm are washed to remove the fluid surrounding them and the rapidly moving sperm separated out.
  • The rapidly moving sperm are placed in a small catheter (tube) to be inserted into the womb.


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Getting ready for IVF- what is reproductive immunology?

“In the 1980s, it became clear to me that products of an activated immune system could damage the placenta and cause miscarriage, as well damage the embryo and cause implantation failure. Natural killer cells, which help to keep the body from developing cancer, can over-populate the uterus or exist at too high levels within the blood stream. These cells than go overboard, killing the embryo or interfering with the endocrine system that produces the hormones that are essential for pregnancy. This response can often be associated with complications for both the mother and her baby if the pregnancy occurs without treatment to suppress the activity of the immune system“.  – Dr. Alan E. Beer (“Is Your Body Baby Friendly?”)

Dr. Alan E. Beer is widely considered as the pioneer in the field of reproductive immunology, he believes that it is not simply due to back luck that some women fail to conceive or have repeated pregnancy failure.

If you have a complex medical and fertility history, and failed fertility treatments, you might want to consider making further tests in advice with your doctor for your immune system. If you have repeated miscarriages, some doctors think that your immune system may be rejecting your pregnancy. So in normal pregnancy, it is thought that your body does something to stop the fetus being rejected. However, there is no convincing evidence that immune rejections of the fetus does actually ever happen in women with fertility problems.

summary of the most relevant testing:

  • Antiphospholipid Antibodies (APA). These are the glue molecules for implantation and placentation.
  • Antinuclear Antibodies (ANA). Some women develop antibodies to the baby’s DNA or DNA breakdown products and this problem is reflected by a positive Anti-nuclear antibody test (ANA). This is often with a speckled pattern. We also advise that women have testing to double-stranded DNA, single-stranded DNA, polynucleotides and histones.
  • Elevated CD 56+ Natural Killer Cells. This test determines the killing power of a woman’s Natural Killer Cells in the test tube. Elevated NK numbers and/or NK activity can be associated with increased risk for infertility and loss.
  • Th1/Th2 Cytokines (chemical messengers in the blood). The immune system is balanced between a TH1 (autoimmune) and TH2 (pregnancy or suppressive response). TH1 predominance can also be associated with reproductive failure. The Th1 Th2 Assay can help to determine a patient’s risk for this problem.
  • T regulatory cells (Treg). Higher numbers of Tregs in the blood have been associated with better pregnancy outcome.
  • Thrombophilias . Thrombophilia is increased tendency to clot.Throughout an entire normal pregnancy, the mother’s ability to produce blood clots in the uterus and the placenta is suppressed. However, in some mothers, this clotting tendency is not suppressed sufficiently. This can contribute to many pregnancy complications.
  • CD57 cells in the endometrium. High levels of CD57+ cells may be associated with increased risk of infertility and loss.

From your circumstances, and medical history, your consultants aim to advice you on the most appropriate tests and treatments for you. Depending on the tests results you will get appropriate immune treatments and medications.

What should I ask my doctor?

If you are recommended immunological treatments as part of your fertility treatment, we advise you to make sure you feel properly informed about the potential benefits and risks of the tests and treatment.

Your clinic should explain:

  • why they think the tests and treatment may help you
  • what the risks and side effects may be
  • the costs you will incur.


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10 proven sperm killers

Want to get pregnant? First you have to know about the 10 proven sperm killers and be prepared for all the things that can go wrong.

Trying to get pregnant is not as easy as everyone think it is. There are lots of things that can go wrong like sperm allergies, poor egg quality and ineffective sperm.  It is proven that one in ten couples are infertile.

Men produce millions of sperm a day. This millions of sperm are nothing compared to the 300-400 eggs that women release during their lifetime. However there are some external factors that can affect the health of these little swimmers. Temperature is one of the reasons that can have big influence on these swimmers, but as we know the sperm cells take about 75 days to grow to maturity. This can also affect your fertility. Check out the 10 proven sperm killers, you might be surprised knowing what may affect a man’s sperm:

High temperature

The function of the human testes is strongly connected with overheating. In order for the human testes not become overheated they need to stay cooler than the rest of the body. The nature has done miracle with this area, male anatomy is designed to create a distance between the testes and the core body temperature. It well known that if the temperature of the testicles is raised to 98 degrees than the sperm production is interrupted. Overheating of the testicles and interrupted sperm production can have a negative impact for months.

Hot tub relaxation

There are times when myths become reality. One of those cases is the influence of the hot tubes and Jacuzzi over the sperm production. More than 30 minutes in a hot tub or in a Jacuzzi can temporarily decrease the sperm production? Now how can that be true?

It is because of the wet heat exposure. If a man exposes himself to a wet heat, it may have an impact on his sperm for a long time. A man’s sperm takes long time to mature, and if he does anything that will reduce this time, it may take six to nine months to show any benefit.

High fever

If there is anything that is most similar and has the same impact to the man sperm, than it is for sure that we are talking about the high fever’s impact on a man’s sperm. It gives the same lasting effects. Generally it depends on the timing in the sperm production process, but the sperm concentration can degrease up to 35% following a fewer.


Leave the laptop on the desk? If you are trying to conceive, you have to know that there is a direct correlation between the laptop use and increased scrotum temperature.  This increase has a harmful effect on the spermatogenesis.


Boxers are better than Briefs

Yes, boxers are better than briefs, but why? It is because if the man is wearing tight bicycle shorts for a long period of time this may affect if the sperm count is on the low side. If the sperm count is normal than it probably affect, but very little.

Enlarged varicose veins

Nearly 15% of men have varicoceles, or enlarged varicose veins in the scrotum. This varicocele veins are usually in the left testicle. With a low sperm count, you may think of a procedure that repairs enlarged varicose veins.

Cell phones

It is better for man to carry their phones is their briefcases rather than in their pockets. If you carry your cell phone in your pocket more than four hours per day, than you may be facing with a lower sperm count in future.


According to the World Health Organization, obese fertile men have reduced testicular function and significantly lower sperm count. Obesity reduces the sperm count and only in some cases obesity may have a negative influence on the male reproductive potential.


It is recommended for those that want to conceive to avoid tobacco, alcohol and marijuana; it can affect the semen quality, production and sperm’s motility.

Other factors

Anti-sperm antibodies, testicular cancer, hormonal imbalance and sexual problems are few of the most dangerous sperm killers.





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40 are the new 30?

Wait, what? 40? Really? Aging really is a state of mind, women in their 40s are looking and feeling better than ever!

Who really buys this idea of 40 being the new 30? As it turns out, women more so than men. In a recent poll, twice as many women vs. men think that 40 is the new 30.

Who doesn’t buy this idea? Not surprisingly, people who have not yet turned 30 definitely don’t think that 40 is the new 30.

We are living faster, getting married later, and having children a decade (or more) later than prior generations. Due to technological innovations and advances in science and medicine, we are improving our health and as a consequence, prolonging our lives. What this means according to scientists, is that middle age is coming on later. But also there is the fact that our body is changing, and we are getting tired easily when we are in our 40s, and we are seeing more of the lines and wrinkles on our faces. So what we should do?

We can magnify imperfections that other people don’t even see, and we should start by not obsessing over everything. We must stop comparing ourselves with other women in general, especially those that we see in the magazines. We are all different and unique, and we must focus on what makes us happy and better, and start focusing on how to take better care of ourselves. Replace the negative remarks with positive, and you will see how amazing you will feel through each day.

Many people become depressed when they hit the big 40, but contary to popular belief, there’s no real reason to fear age 40. It is becoming accepted that a person of this age has fewer limitations with regards to health and lifestyle options than those of previous generations.  People are living longer lives and, with proper lifestyle changes, can be as healthy, fit and vital, not to mention youthful in appearance and physique, for many of these years. All of this posturing to be a decade younger? Are we obsessed with looking and being young? Of course we are. And, there are billion dollar cosmetics, health and fitness industries to prove it. At some point we’ll all come to the grips of aging, it is inevitable, but we should embrace it and make that our strength because with age comes wisdom and grace. We are learning how to get more comfortable in our skin, to focus on what is important in our lives and what makes us happy.
This idea of an older decade being the ‘new’ younger decade is not a novel concept. It was first tossed years ago when stars like Sheryl Crow, Courtney Cox and Sarah Jessica Parker turned the big 40. Now that more of our most adorable starlets–Gwen Stefani, Jennifer Lopez, Jennifer Aniston, Renee Zellweger and Taraji Henson, along with many of our leading men–Matt Damon, Vince Vaughn, Tyson Beckford, Ethan Hawke, and Malcolm Jamal Warner–have hit that number in the last couple of years, Hollywood, the fashion industry, the media and, yes, the world are rethinking the way we look at those over 40.

Maybe that explains it. It’s all a matter of perspective or is this just our way of making aging more acceptable? What do you think?


Loose Vagina – Questions and Answers

Hello ladies

A loose vagina is not something that happens over night and then goes away the next day and I am here to inform you that you are not the only one with this problem. There are many more like you and some of us are even born with it. Having a loose vagina can make you lose your confidence which we don’t want to happen. The following is an explanation of what caused loose vagina and a non-invasive easy way to tighten it.

What causes a loose vagina?

The vagina is made of muscles which relax and contract. The vaginal muscles also link to other organs and muscles. Those links, which hold the vagina tight, can wear over time. That is why women between the ages of 30 to 40 years old and women over 65 are more likely to experience a loosening of the vaginal muscles.

Women who are 30 to 40 are included in this group because they are of reproductive age and typically have given birth to one or more children. Some of them have also had medical interventions, either by having abortions or other kinds of surgery. Although they are far from menopause, they are still sexually active and using their vaginal muscles. Women who are over 65 are more likely that have decreased muscle thickness, a thinner pelvic floor and the links between their bladder and other organs are weakened over time. That is why older women are more likely suffer from urinary incontinence as well.

What about with women who are sexually inactive or that have no children?

Young girls may also have a loose vagina. Beside the fact, sex isn’t always the cause. If young girls use tampons during each menstrual cycle, then vaginal stretching could occur in smaller females. Some females have a naturally larger pelvis which may also be the cause of a loose vagina from an early age.

For women that do not have children, haven’t had an abortion and haven’t had any other medical intervention, it is assumed that their sex life is the reason. When I was reading about relationships and loose vaginas there was one case that caught my attention. In this case, a woman who had ended a two year relationship had then been sexually inactive for six months. She then started to date a new boyfriend and after they had made love for the first time, he told her that she had a loose vagina. She needed help. When women have been in a relationship and have a loose vagina, it is assumed that they got used to being with their previous partner and the muscles of their vagina have stretched to conform to having sex with that person. Regardless as to whether you are in a relationship, married or single, there are ways to prevent this problem. In searching for an answer it is, however, easy to find false information that will catch your attention and steer you in the wrong direction.



Some myths about loose vagina

Many women will hear the following myths telling them ways to prevent having a loose vagina or what will happen if you have one.

  • not sacrificing your vagina,
  • do not have lots of sex after you have a baby,
  • not having an angry husband to remind you every day that your vagina is too big

First, I will talk about ‘not sacrificing your vagina’. Many women would rather choose a cesarean delivery rather than natural childbirth, thinking that natural childbirth causes loose vaginas. Well I would like to inform you that you are potentially making the wrong choice. An unnecessary cesarean delivery is opting for an elective surgery. When a woman has a cesarean delivery the uterine muscles will need more time to get back into shape from being cut open. Many women don’t realize that the soft maternity road of the vagina needs time to contract too (whether the baby went through or not). The vagina opens up (but the cervix sometimes doesn’t which is a common reason for an unelected cesarean delivery) which means that there is no blood going through, no baby passing through and it takes more time for the brain to tell the vagina that it needs to make contractions in order to get back into shape.

When you tell a woman that too much sex leads to a loose vagina, it will potentially lead her to the wrong conclusion. A woman may think that if she has too much sex then she should have less sex in order to not have a loose vagina. It doesn’t work that way. This is only for promiscuous women that like to put large objects inside or who have a lot of sex all of the time.

How do I find out if I have a loose vagina?

The symptoms of a loose vagina are very clear. Women with a loose vagina have a hard time achieving an orgasm. Their vaginal muscles do not contract as much during or after sex. As a result, their sex life has become disappointing and unfulfilling. The only way for you to figure it out is by putting your index finger inside your vagina to find out if there seems to be a lot of space inside. Most women lose their confidence in bed when they find out they have a loose vagina.

Many women do not want to have vaginal reconstructive surgery or do not feel that Kegel exercises are the solution. That is why many women search for another answer to this problem.


Aside from Kegel exercises and Vagina reconstructive surgery, are there any other permanent solutions?


A vaginal rejuvenating gel might be a solution to this problem. This life long solution can bring back your confidence in bed and make your vagina tight again. The VIVAVIA Vaginal Rejuvenating Gel gives fabulous results to women who have a loose vagina. It is a lovely, sumptuous, nourishing gel that is not too heavy for intimate hygiene. It is Ph balanced for the sensitive vaginal area, containing anti-irritant ingredients that protect and soothe the skin. This gel will help you tighten your vaginal muscles and protect the vaginal area from infections. VIVAVIA is derived from natural ingredients that are blended with certified botanicals.

The purpose of this gel is to hydrate the internal vaginal walls and create a youthful tightening effect. VIVAVIA rejuvenates women who suffer from loose vagina and take their arousal to new levels.

The VIVAVIA Vaginal Rejuvenating Gel is a safe product made of botanical ingredients, manufactured in Malmö, Sweden just to ensure the high quality of this product. Some great features of this herbal-based gel are:

  • Fast by acting with long lasting effects
  • Mild and non-irritating
  • Comfortable and easy to use

We all need a solution that is natural. I have been reading about other solutions that are offered to women and the difference is that this gel is safe and easy to use. VIVAVIA is a product made from all-natural ingredients and used to stimulate the reversal of time by reducing the interior dimensions of the vagina. Once the tightness is back, the feeling of sexual gratification will be back too.

VIVAVIA’s Vaginal Rejuvenation Gel’s secret ingredients

Many product makers keep their special ingredients a secret. However, the makers of VIVAVIA Vaginal Rejuvenation Gel feel that it’s important to share theirs: Imidazollidinyl Urea, Hydroxyethyl Cellulose, Trethanolamine, Carbomer, Allantoin, Phenoxyethanol, Methylparaben, Butylparaben, Ethylparaben, Propylparaben, Aqua (Chamomilla Recutita). These ingredients are mixed with love, to support all women whom have a loose vagina, in order to achieve a solution that is life changing.

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NCLEX requirements – Some things you need to know about this exam

Few words about the NCLEX that can help you pass

Nursing is a noble profession which corresponds to the human nature and need to help other humans. But one cannot do it with just a desire to help. There are some requirements to fulfill to do it professionally. That’s way there are millions of applicants every year that take the NCLEX (National Council Licensure Examination) in order to become a certified nurse. The test is designed to see your knowledge and significant skills as a potential nurse. Your capability to care, right judgment in a right moment, and opinion of something that should or shouldn’t be done is put to the test. This test is purposefully difficult so only the qualified applicants will pass. The health promotion, safe care environment, or how to properly perform CPR, are few examples of the topics in the NCLEX. There are multiple choice questions followed by an alternative type items. Here is an example about three diabetes questions that might help you understand the NCLEX:

1. Albert, a 35-year-old insulin dependent diabetic, is admitted to the hospital with a diagnosis of pneumonia. He has been febrile since admission. His daily insulin requirement is 24 units of NPH. Every morning Albert is given NPH insulin at 0730. Meals are served at 0830, 1230, and 1830. The nurse expects that the NPH insulin will reach its maximum effect (peak) between the hours of:

A. 1130 and 1330

B. 1330 and 1930

C. 1530 and 2130

D. 1730 and 2330

2. A bedtime snack is provided for Albert. This is based on the knowledge that intermediate-acting insulins are effective for an approximate duration of:

A. 6-8 hours

B. 10-14 hours

C. 16-20 hours

D. 24-28 hours

3. Albert refuses his bedtime snack. This should alert the nurse to assess for:

A. Elevated serum bicarbonate and a decreased blood pH.

B. Signs of hypoglycemia earlier than expected.

C. Symptoms of hyperglycemia during the peak time of NPH insulin.

D. Sugar in the urine

(If you are wondering, the answers are B, C and B)

How can you prepare for the NCLEX?

It is more convenient to take the NCLEX within a month of your graduation from nursing school. Usually you need to spend at least three hours daily studying prior to the test. Always review the NCLEX tutorials and spend as much time on the practice exams. The online resources are the best place where you can find everything that you need to know about this exam. Go to the official web site and feel free to seek for as much information as you can. When I was taking the NCLEX, my best friend in the process to kill the anxiety was the good night sleep, before the exam. The only thing you should know about this test is: there is no “Good Luck”. You have to prepare for it. Do not worry about those that failed, you are not one of them!

Your NCLEX testing day has begun

Do not forget to bring your photo identification and your Authorizations to Test (ATT) form. Without the form and the photo identification you cannot take the exams. The receptionist will give you a number and a key to a locker to store all your belongings. Before you enter the room you will be fingerprinted and the administrator is going to keep an eye on you while a camera is directed on each person. If you have to use the restroom, you will be escorted out by the administrator.

The NCLEX test is 6 hours long journey packed with 265 questions on the NCLEX-RN and 205 questions on the NCLEX-PN. You can take a break if you feel tired. But then the time is deducted from your total time. After you’re done your photo identification will be returned and you can find out if you passed the test within forty-eight hours. If you failed the NCLEX, you can take it again, but you must wait a minimum of 45 days.

Most people are asking themselves if they will earn more if they pass the NCLEX, you can post more questions about this subject, or Do they need a license to pass medications?


Are you the right candidate for Lasik Surgery?

JANA2Wearing glasses or contact lenses makes you wonder if maybe a Lasik Surgery could be the right choice for you. Yes, the Lasik Surgery gives the best results today and it can reduce or eliminate the need for corrective lenses, but it still remains the question: Are you the right person for this procedure?

Like any other medical procedure the Lasik Surgery carries its own risks and it may not be the most appropriate vision-correction for everyone. If you want to find out if you are the right person for this procedure keep on reading to determine:

When a Lasik Surgery can be a good choice?

A type of refractive surgery is a Lasik Surgery. During this procedure the eye surgeon will create a flap in the cornea and he will use a laser to reshape the cornea in order to correct the focusing problems in the eye. That is why Lasik Surgery is most appropriate for people who have a moderate degree of:

Nearsightedness or myopia- you can see nearby objects clearly, but those objects that are distant are blurry

Farsightedness or hyperopia- you can see the distant objects clearly, but those objects that are nearby are blurry

Astigmatism- this is a condition of a blurry vision

Can I have a Lasik Surgery for presbyopia?

Most adults may lose their ability to focus on nearby objects (presbyopia), and their condition may continue to worsen until the age of 65. If you have a difficulty to see nearby objects you have to know that the Lasik Surgery will give you clear distance vision, but you may not be able to see objects close up.

Monovision is a procedure that will maintain your ability to see close objects. With this procedure, one eye is corrected for distant vision and the other eye for near vision. Not everyone can agree with this procedure, the best choice still remains to do a trial with contact lenses until having a permanent surgical procedure.


Like any other surgery the Lasik surgery has its own risks too:

Under-correction, astigmatism or overcorrection: Removing too much tissue from your eye will bring you negative results, or you will not get the clearer vision you wanted. The same result you will get with uneven tissue removal which can result in astigmatism.

Vision disturbances: This can happen after the surgery, you may have difficulty seeing at night. Double vision, glare, halos around bright light are few of the vision disturbances that you may notice after the surgery.

Dry eyes: Until your eyes completely heal you may feel them unusually dry. The Lasik Surgery can cause a temporary decrease in the tear production.

Flap problems: A rare complication which can happen while folding back or removing the flap from the front of the eye during the surgery. This can cause complications, infections, excess tears and swelling.